Publications

Publications by the Clinical Breast Care Project  (Past 5 years)

Manuscripts
Rummell-SK, Lovejoy-LA, Turner-CE, Shriver-CD, Ellsworth-RE. Should genetic testing for cancer predisposition be standard-of-care for women with invasive breast cancer: the Murtha Cancer Center experience. Published in Cancers journal. Cancers 2020, 12-234; doi10.3390.
Abstracts
Wang-G, Shah-P, Tolstikov-V, Raj-Kumar-PK, Liu-J, Sturtz-LA, Campbell-L, Zingmark-R, Hooke-J, Cutler-M, Richardson-K, Rodrigues-L, Bussberg-V, Sarangarajan-R, Kiebish-MA, Hu-H, Narain-NR, Kovatich-AJ, Shriver-C. Integrated Proteomic and Informatic Assessment of ER+ and ER- Breast Tumors Validated by CPTAC and TCGA Data. Approved for presentation at the American Association of Cancer Research (AACR) annual meeting, April 24-29, 2020,

San Diego, CA. Rummel SK, Lovejoy LA, Turner CE, Shriver CD, Ellsworth RE. Should genetic testing for cancer predisposition be standard of care for women with invasive breast cancer: the Murtha Cancer Center experience. Approved for submission to the American Association for Cancer Research (AACR) annual meeting, 24-29 April, 2020, San Diego, CA.

August 2020 Military Health System Research Symposium (MHSRS), August 2020: Raj Kumar-PK, Sturtz-LA, Kovatich-AJ, Deyarmin-B, Hooke-JA, Fantacone Campbell-L, Praveen Kumar-A, Liu-J, Craig-J, Kvecher-L, Kane-J, Melley-J, Somiari-S, Benz-SC, Golovato-J, Rabizadeh-S, Soon-Shiong-P, Mural-RJ, Shriver-CD, Hu-H. Validation of laser microdissected primary breast tumors for RNA-Seq over bulk processing with cohort control. Rummel-SK, Lovejoy-LA, Turner-CE, Shriver-CD, Ellsworth-RE. Should genetic testing for cancer predisposition be standard-of-care for women with invasive breast cancer? The Murtha Cancer Center
experience. Lovejoy-LA, Wolinsky-R, Shriver-CD, Ellsworth-RE. Do reproductive choices in active-duty servicewomen contribute to increased risk of breast cancer? Lovejoy-LA, Shriver-CD, Ellsworth-RE. Cancer previvors within active-duty service women population: an opportunity for prevention and increased Force Readiness. Wang-G, Shah-P, Tolstikov-V, Raj Kumar-PK, Liu-J, Sturtz-LA, Somiari-S, Deyarmin-B, Campbell-L, Zingmark-R, Hooke-J, Cutler0ML, Granger-E, Richardson-K, Rodrigues-L, Bussberg-V, Sarangarajan-R, Narain-NR, Hu-H, Kiebish-MA, Kovatich-AJ, Shriver-C. Integrated Proteomic and Informatic Assessment of ER+/HEr2- and Er-/HER2- Breast Tumors.

Jie Lin, Christine Kamamia, Derek Brown, Stephanie Shao, Katherine A. McGlynn, Joel A. Nations, Corey A. Carter, Craig D. Shriver, and Kangmin Zhu, "Survival among Lung Cancer Patients in the U.S. Military Health System: A Comparison with the Seer Population." Cancer Epidemiology, Biomarkers& Prevention, June 2018

Liu J, Lichtenberg T, Hoadley KA, Poisson LM, Lazar AJ, Cherniack AD, Kovatich AJ, Benz CC, Levine DA, Lee AV, Omberg L, Wolf DM, Shriver CD, Thorsson V; Cancer Genome Atlas Research Network, Hu H, "An Integrated TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR) to drive high quality survival outcome analytics." Cell, April 2018

Alexandra S. Zimmer, Kangmin Zhu, Patricia S. Steeg, Alex Wu, Margaret Gatti-Mays, Sanaz Soltani, Jeremy Perkins, Stephanie Shao, Derek Brown, Matt Georg , Hai Hu, Craig D. Shriver, Stanley Lipkowitz,"Analysis of Breast Cancer in Young Women in the Department of Defense (DOD) Database." Breast Cancer Research and Treatment, April 2018

Praveen-Kumar Raj-Kumar, Tao Liu, Lori A. Sturtz, Albert J. Kovatich, Marina A. Gritsenko, Vladislav A. Petyuk, Brenda Deyarmin, Viswanadham Sridhara, James Craig, Jason E. McDermott, Anil K. Shukla, Ronald J. Moore, Matthew E. Monroe, Bobbie-Jo M. Webb-Robertson, Jeffrey A. Hooke, Leigh Fantacone-Campbell, Leonid Kvecher, Jianfang Liu, Jennifer Kane, Jennifer Melley, Stella Somiari, Stephen C. Benz, Justin Golovato, Shahrooz Rabizadeh, Patrick Soon-Shiong, Richard D. Smith, Richard J. Mural, Karin D. Rodland, Craig D. Shriver, Hai Hu.  Integrated proteogenomic analysis of laser microdissected primary breast tumors define proteome clusters.  American Association of Cancer Research annual conference, Chicago, IL.  April 2018

Matthew D. Wilkerson, Clifton L. Dalgard, Craig D. Shriver, Rachel E. Ellsworth. “Improved understanding of the etiology of breast cancer in young women through evaluation of the genomic landscape,” Military Health System Research Symposium, August, 2018 (abstract/oral presentation, WRNMMC PAO approved April 3, 2018).

Meera Srivastava, Alakesh Bera, Ofer Eidelman, Michael Eklund, Matthew Hueman, Harvey B. Pollard, Hai Hu, Craig Shriver. “Proteomic analysis of inflammatory biomarkers associated with breast cancer recurrence,” Military Health System Research Symposium, August, 2018 (abstract/oral presentation, WRNMMC PAO approved April 3, 2018).

Yvonne L Eaglehouse, Matthew Georg, Patrick Richard, Craig D. Shriver, Kangmin Zhu. “Costs for Breast Cancer Care in the U.S. Military Health System: An Analysis by Benefit Type and Care Source,” Military Health System Research Symposium, August, 2018 (abstract/oral presentation, WRNMMC PAO approved March 28, 2018).

Yvonne L. Eaglehouse, Matthew W. Georg, Craig D. Shriver, Kangmin Zhu. “Time to Surgery and Overall Survival: Comparison of Black and White Women Diagnosed with Breast Cancer in the U.S. Military Health System,” Military Health System Research Symposium, August, 2018 (abstract/oral presentation, WRNMMC PAO approved March 28, 2018).

Leann Lovejoy, Craig Shriver, Rachel Ellsworth. “Population screening for BRCA1 and BRCA2 mutations: results from a feasibility study within a military treatment facility,” (manuscript submission, WRNMMC PAO approved March 23, 2018).

Yvonne L Eaglehouse, Matthew Georg, Patrick Richard, Craig D. Shriver, Kangmin Zhu. “The continuum of breast cancer care and outcomes in the U.S. Military Health System: an analysis by benefit type and care source,” J Cancer Surviv. 2018 Feb 17. doi: 10.1007/s11764-018-0680-1

Praveen-Kumar Raj-Kumar, Jianfang Liu, Albert J. Kovatich, Leonid Kvecher, Craig D. Shriver, Hai Hu. “Use of principal components to select a gene expression-based ER-balanced subset for gene centering in PAM50 subtyping,” Intelligent Systems for Molecular Biology (manuscript submission, WRNMMC PAO approved February 16, 2018).

Leann A. Lovejoy1, Craig D. Shriver2, Rachel E. Ellsworth. “Mutational spectrum across 94 cancer predisposition genes in patients with TNBC,” (manuscript submission, WRNMMC PAO approved January 12, 2018).

Zimmer A, Kangmin Z, Patricia S,  Wu A, Gatti-Mays M, Soltani S, Perkins J, Shao S, Brown D, Georg M, Hu H,  Shriver C, Lipkowitz S. “Analysis of Breast Cancer in Young Women in the Department of Defense (DOD) Database,” Breast Cancer Res Treatment, 2017 Dec 15. doi: 10.1007/s10549-017-4615-8. (published

Jianfang L, Lichtenberg L, Hoadley K, Poisson L, Lazar A, Cherniack A, Kovatich A, Benz C, Levine D, Lee A, Omberg L, Wolf D, Shriver C, Thorsson V, The Cancer Genome Atlas Research Network, Hu H. “An Integrated TCGA Pan-Cancer Clinical Data Resource (TCGA-CDR) to drive high quality survival outcome analytics.” (manuscript submission WRNMMC PAO approved December 12, 2017)

Lovejoy L, Shriver C, Ellsworth R. “Mutational spectrum across 94 cancer predisposition genes in patients with TNBC.” (manuscript submission WRNMMC PAO approved December 11, 2017)

Kumar AP, Kovatich AJ, Biancotto A, Cheung F, Davidson-Moncada JK, Kvecher L, Liu J, Ru Y, Kovatich AW, Deyarmin B, Fantacone-Campbell JL, Hooke JA, Raj Kumar PK, Rui H, Hu H, Shriver CD. “Analysis of breast cancer recurrence using gene set enrichment analysis,” Presented at the San Antonio Breast Cancer Symposium, San Antonio, TX, December 5-9, 2017. (abstract/oral presentation)

Raj-Kumar PK, Liu J, Kovatich AJ, Kvecher L, Shriver CD, Hu H. “Use of principal component analyses to select ER-balanced subset for gene centering in PAM50 subtyping,” Presented at the San Antonio Breast Cancer Symposium, San Antonio, TX, December 5-9, 2017. (abstract/oral presentation)

Liu J, Lichtenberg T, Hoadley K, Cherniack A, Poisson L, Kovatich A, Benz C, Thorsson V, PanCanAtlas Network, Shriver CD, Hu H. “Using the new Pan-Cancer Clinical Data Resource (TCGA-CDR) to identify breast cancer genomic correlates associating with different survival outcome endpoints,” Presented at the San Antonio Breast Cancer Symposium, San Antonio, TX, December 5-9, 2017.  (abstract/oral presentation)

Chaudhary, L. N., Peck, A. R., Yunguang, S., Hu, H., Kovatich, A. J., Hook, J. A., Shriver, C. D., Mitchell, E. P., Chervoneva, I. and Rui, H. (2017) 'High levels of Bruton's tyrosine kinase (BTK) protein is associated with favorable outcome in breast cancer', 40th San Antonio Breast Cancer Symposium. San Antonio, TX, December 5 - 9, 2017.

Ellsworth D, Blackburn H, Shriver C, Rabizadeh S, Soon-Shiong P, Ellsworth R. “Single-cell sequencing and tumorigenesis: improved understanding of tumor evolution and metastasis.” Clin Transl Med. 2017 Dec;6(1):15. doi: 10.1186/s40169-017-0145-6 (published)

Tran T, Utama F, Sato T, Peck A, Sun Y, Langenheim J, Udhane S, Liu C, Girondo M,  Kovatich A, Hooke J, Shriver C, Hu H, Palazzo J, Bibbo M,  P, Flister M, Rimm D, Hyslop T, Mitchell E, Chervoneva I, Rui H.  “Loss of nuclear localized Parathyroid Hormone-related Peptide in primary breast cancer predicts poor clinical outcome and is associated with suppressed Stat5 signaling.” (manuscript submission WRNMMC PAO approved November 9, 2017)

Panel testing to evaluate genetic predisposition to breast cancer in African American women. American Association of Cancer Research Tenth Conference on the Science of Cancer Health Disparities in Racial/Ethnic Minorities and the Medically Underserved. September 25-28, 2017

A Data Tracking System for the Clinical Breast Care Project (DTS-CBCP). Military Health System Research Symposium in Kissimmee, FL. August 2017

Abundance and distribution of organochlorine pesticide residues in breast tissue from women in the Clinical Breast Care Project. Military Health System Research Symposium in Kissimmee, FL. August 2017

Effects of smoking on breast tumor pathology. Military Health System Research Symposium in Kissimmee, FL. August 2017

Contribution of germline mutations in cancer predisposition genes to tumor etiology in young women diagnosed with invasive breast cancer. Military Health System Research Symposium in Kissimmee, FL. August 2017

Outcome disparities in African American compared to European American women with ER+HER2- tumors treated within an equal-access health care system. Military Health System Research Symposium in Kissimmee, FL. August 2017

Breast Health, Breast Cancer, and Readiness of the Active Duty Force. Military Health System Research Symposium in Kissimmee, FL. August 2017

Liu J, Lichtenberg T, Hoadley K, Cherniack A, Poisson L, Kovatich A, Benz C, Thorsson V, PanCanAtlas Network, Shriver CD, Hu H. “Using the new Pan-Cancer Clinical Data Resource (TCGA-CDR) to identify breast cancergenomic correlates associating with different survival outcome endpoints.” Ready to be submitted to DRP for publication clearance on 15 June 2017 to be presented at the 2017 San Antonio Breast Cancer Symposium.

Raj-Kumar PK, Liu J, Kovatich AJ, Kvecher L, Shriver CD, Hu H. “Use of principal component analyses to select ER-balanced subset for gene centering in PAM50 subtyping.” Ready to be submitted to DRP for publication clearance on 15 June 2017 to be presented at the 2017 San Antonio Breast Cancer Symposium.

Kumar AP, Kovatich AJ, Biancotto A, Cheung F, Davidson-Moncada JK, Kvecher L, Liu J, Ru Y, Kovatich AW, Deyarmin B, Fantacone-Campbell JL, Hooke JA, Raj Kumar PK, Rui H, Hu H, Shriver CD. “Analysis of breast cancer recurrence using gene set enrichment analysis.” Ready to be submitted to DRP for publication clearance on 15 June 2017 to be presented at the 2017 San Antonio Breast Cancer Symposium.

Lovejoy LA, Shriver CD, Ellsworth RE. “Assessment of the hereditary component in 94 cancer predisposition genes to triple negative breast cancer.” Submitted to DRP for publication clearance on 23 May 2017.

Eaglehouse YL, Shao S, Chan W, Brown D, Manjelievskaia J, Shriver CD, Zhu K. “The continuum of breast cancer care and outcomes in the U.S. Military Health System: an analysis by benefit type and care source.” Publication clearance received on 23 May 2017 to be presented at the 2017 Military Health System Research Symposium.

Raj Kumar PK, Liu T, Sturtz LA, Kovatich AJ, Gritsenko MA, Petyuk VA, Deyarmin B, Sridhara V, Craig J, McDermott JE, Shukla AK, Moore RJ, Monroe ME, Webb-Robertson BM, Hooke JA, Fantacone-Campbell L, Kvecher L, Liu J, Kane J, Melley J, Somiari S, Iida J, Benz SC, Golovato J, Rabizadeh S, Soon-Shiong P, Smith RD, Mural RJ, Rodland KD, Shriver CD, Hu H. “Differential exon usage in the HER2 subtype of breast cancer identified with RNA-seq and proteomic data.” American Association for Cancer Research Annual Meeting, 2017 Apr 1-5, Washington, D.C.

Sridhara V, Liu T, Gritsenko, MA, Sturtz LA, Kovatich AJ, Petyuk VA, Deyarmin B, McDermott JE, Shukla AK, Moore RJ, Monroe ME, Webb-Robertson BM, Hooke JA, Fantacone-Campbell L, Raj Kumar PK, Kvecher L, Liu J, Kane J, Melley J, Somiari S, Iida J, Benz SC, Golovato J, Rabizadeh S, Soon-Shiong P, Smith RD, Mural RJ, Shriver CD, Hu H, Rodland KD. “Integrated proteogenomic analysis of laser capture microdissected breast tumors.” American Association for Cancer Research Annual Meeting, 2017 Apr 1-5, Washington, D.C.

Costantino N, Shriver CD, Ellsworth RE. “Effects of smoking on breast tumor pathology.” Presented at the American Association for Cancer Research Annual Meeting, 2017 Apr 1-5, Washington, D.C.

Manjelievskaia J, Brown D, Shao S, Hofmann K, Shriver CD, Zhu K. “Benefit Type and Care Source in Relation to Mammography Screening and Breast Cancer Stage at Diagnosis Among DoD Beneficiaries.” Military Medicine 182(3): March 2017.

Blackburn HL, Ellsworth DL, Shriver CD, Ellsworth, RE. “Breast Cancer Metastasis to the Axillary Lymph Nodes: Are Changes to the Lymph Node “Soil” Localized or Systemic?” Breast Cancer: Basic and Clinical Research 10 Feb 2017.

Costantino NS, Cox TM, Shriver CD, Ellsworth RE. “Lifestyle and Reproductive Factors Associated with Breast Cancer Risk in Young Women.” EC Gynaecology 4(2): 36-45. 08 Feb 2017.

Rummel SK, Shriver CD, and Ellsworth RE.  Contribution of germline mutations in cancer predisposition genes to tumor etiology in women diagnosed with invasive breast cancer before 40 years.  San Antonio Breast Cancer Symposium, 2016 Dec 6-12, San Antonio, TX.

Iida J, Dorchak J, Slavik J, Clancy R, Cutler ML, Shriver CD.  NEDD9 promotes breast cancer metastasis by regulating mitochondrial functions.  San Antonio Breast Cancer Symposium, 2016 Dec 6-12, San Antonio, TX.

Huo D, Hu H, Rhie SK, Gamazon EG, Cherniack AD, Liu J, Yoshimatsu TF, Pitt JJ, Hoadley KA, Ru Y, Lichtenberg T, Sturtz L, Laird PW, Shriver CD, Perou CM and Olopade OI.  Comprehensive Comparison of Breast Cancer Molecular Portraits between Black and White Patients in The Cancer Genome Atlas.  San Antonio Breast Cancer Symposium, 2016 Dec 6-12, San Antonio, TX.

Lovejoy L, Constantino N, Shriver CD, Ellsworth RE.  Relationship between obesity and breast tumor pathology in a contemporary set of patients.  San Antonio Breast Cancer Symposium, 2016 Dec 6-12, San Antonio, TX.

Peck AR, Girondo MA, Liu C, Kovatich AJ, Hooke JA, Shriver CD, Hu H, Mitchell EP, Freydin B, Hyslop T, Chervoneva I, Rui H.  Robustness of quantitative immunohistochemistry: benchmark validation of two distinct automated immunofluourescence image analysis platforms.  San Antonio Breast Cancer Symposium, 2016 Dec 6-12, San Antonio, TX.

Peck AR, Girondo MA, Liu C, Kovatich AJ, Hooke JA, Shriver CD, Hu H, Mitchell EP, Freydin B, Hyslop T, Chervoneva I, Rui H.  Validation of tumor protein marker quantification by two independent automated immunofluorescence image analysis platforms. Mod Pathol.  2016 Oct;29(10):1143-54.

Costantino NS, Cox TM, Shriver CD, Ellsworth RE.  Lifestyle and reproductive factors associated with breast cancer risk in young women. WRNMMC publication clearance approval, 31 October 2016.

Blackburn, HL, Ellsworth, DL, Shriver CD, Ellsworth RE.  Breast cancer metastasis to the axillary lymph nodes: are changes to the lymph node “soil” localized or systemic?  WRNMMC publication clearance approval, 31 October 2016.

Costantino NS, Shriver CD, Ellsworth RE.  Effects of smoking on breast tumor pathology.  WRNMMC publication clearance approval, 25 October 2016.

Liu J, Kovatich AJ, Hooke JA, Campbell-Fantacone JL, Kvecher L, Sturtz LA, Shriver CD, and Hu H.  Race is not a contributing factor to breast cancer-free interval outcome for patients treated at the Walter Reed National Military Medical Center.  2016 Military Health System Research Symposium, 2016 Aug 15-18, Kissimmee, FL.

Ellsworth RE, Blackburn HL, Shriver CD, Soon-Shiong P, Ellsworth DL.  Molecular heterogeneity in breast cancer: state of the science and implications for patient care.  Semin Cell Dev Biol.  2016 Aug 26. pii: S1084-9521(16)30266-X.

Constantino N, Freeman B, Shriver CD, Ellsworth RE.  Outcome disparities in African American compared to European American women with ER+HER2- tumors treated within an equal-access health care system.  Ethnicity and Disease, 2016 Jul 21; 26(3):407-16.

Sabino J, Lucas DJ, Shriver CD, Vertrees AE, Valerio IL, Singh DP.  NSQIP analysis: increased immediate reconstruction in the treatment of breast cancer. Am Surg. 2016 Jun;82(6):540-5.

Brown D, Shao S, Jatoi I, Shriver CD, Zhu K.  Trends in use of contralateral prophylactic mastectomy by racial/ethnic group and ER/PR status among patients with breast cancer: A SEER population-based study.  Cancer Epidemiol.  2016 Jun; 42:24-31.

Peck AR, Girondo MA, Liu C, Kovatich AJ, Hooke JA, Shriver CD, Hu H, Mitchell EP, Freydin B, Hyslop T, Chervoneva I, and Rui H. Validation of tumor protein marker quantification by two independent automated immunofluorescence image analysis platforms.  Mod Pathol. 2016 Jun 17.

Schwartzberg BS, Abdelatif O, Lewin J, Bernard J, Bu-Ali H, Cawthorn S, Chen-Seeto M, Feldman SM, Govindarajulu S, Jones L, Juette A, Kavia S, Maganini R, Pain S, Shere M, Shriver CD, Smith S, Valencia A, Whitacre EB, and Whitney R.  Multicenter, phase II open-label trial of percutaneous laser ablation (PLA) for 61 patients (PTS) with early-stage (ES) primary breast cancer: radiographic (MRI) and pathological correlation.”  J Clin Oncol 34, 2016 (suppl; abstr e12525).  Published in conjunction with the American Society of Clinical Oncology (ASCO) Annual Meeting, 3-7 Jun 2016, Chicago, IL.

Toro AL, Costantino NS, Shriver CD, Ellsworth DL, and Ellsworth RE.  Effect of obesity on molecular characteristics of invasive breast tumors: gene expression analysis in a large cohort of female patients.  BMC Obes. 2016 Apr 29:3:22.

Goodman CR, Sato T, Peck AR, Girondo MA, Yang N, Liu C, Yanac AF, Kovatich AJ, Hooke JA, Shriver CD, Mitchell EP, Hyslop T, Rui H. Steroid induction of therapy-resistant cytokeratin-5-positive cells in estrogen receptor-positive breast cancer through a BCL6-dependent mechanism. Oncogene. 2016 Mar 17;35(11):1373-85. doi: 10.1038/onc.2015.193.  Epub 2015 Jun 22.

Rummel, SK, Ellsworth RE.  The role of histoblood ABO group in cancer.  Future Science OA.  2016 Mar 15.  FSO107.

Iida J, Bell-Loncella ET, Purazo ML, Lu Y, Dorchak J, Clancy R, Slavik J, Cutler ML, Shriver CD. Inhibition of cancer cell growth by ruthenium complexes. J Transl Med. 2016 Feb 12;14(1):48. doi: 10.1186/s12967-016-0797-9.

Costantino N, Toro AL, Shriver CD, Ellsworth DL, Ellsworth RE.  “Can a diagnosis of invasive breast cancer effectively motivate patients to follow a healthy lifestyle?”  San Antonio Breast Cancer Symposium, San Antonio, TX, 8-15 DEC 2015.

Toro AL, Costantino NS, Shriver CD, Ellsworth DE, Ellsworth R.  “Effect of obesity on molecular characteristics of invasive breast tumors; gene expression analysis of 405 tumors by BMI.”  San Antonio Breast Cancer Symposium, San Antonio, TX, 8-15 DEC 2015.

Ru Y, Hu PT, Kovatich AJ, Hooke JA, Jianfang L, Kvecher L, Fantacone-Campbell  JL, Deyarmin B, Kovatich AW, Cammarata F, Rui H, Shriver CD, Hu H. “CD163 expression is associated with young age, triple negative subtype, and poor outcome in breast cancer.”  San Antonio Breast Cancer Symposium, San Antonio, TX, 8-15 DEC 2015.

Iida J, Dorchak J, Clancy R, Slavik J, Cutler M, Shriver C,  “Tumor-associated glycans as key molecules to promote triple-negative breast cancer cells.”  San Antonio Breast Cancer Symposium, San Antonio, TX, 8-15 DEC 2015.

Craig J, Kovatich AJ, Hooke JA, Kvecher L, Liu J, Fantacone-Campbell JL, Rui H, Shriver CD, Hu H.  “PhosphohistoneH3 as a prognostic marker in breast cancer: high expression is associated with younger age, triple negative subtype, and disease specific survival.”  San Antonio Breast Cancer Symposium, San Antonio, TX, 8-15 DEC 2015.

Constantino N, Freeman B, Shriver CD, Ellsworth RE.  “Outcome disparities in African American compared to European American women with ER+HER2- tumors treated within an equal-access health care system.”  Submitted for publication in the journal, Ethnicity and Disease, 20 Nov 2015.

Kovatich AJ, Chen Y, Hooke JA, Kvecher L, Liu J, Bekhash A, Maskery S, Fantacone-Campbell JL, Ru Y, Rui H, Mural RJ, Shriver CD, Hu H.  “Subtype-specific co-occurrence of atypical hyperplasia and in situ carcinoma with invasive breast cancers.”  Submitted for publication in the journal, Cancer Epidemiology, Biomarkers and Prevention, 18 Nov 2015.

Toro AL, Hueman MT, Shriver CD, Ellsworth RE.  “Epidemiological factors associated with breast cancer in young women.”  Submitted for WRNMMC publication approval 6 Nov 2015.

Ciriello G, Gatza ML, Beck AH, Wilkerson MD, Rhie SK, Pastore A, Zhang H, McLellan M, Yau C, Kandoth C, Bowlby R, Shen H, Hayat S, Fieldhouse R, Lester SC, Tse GM, Factor RE, Collins LC, Allison KH, Chen YY, Jensen K, Johnson NB, Oesterreich S, Mills GB, Cherniack AD, Robertson G, Benz C, Sander C, Laird PW, Hoadley KA, King TA, TCGA Research Network, Perou CM.  “Comprehensive molecular portraits of invasive lobular breast cancer.”  Cell. 2015 Oct 8;163(2):506-19.

Valente AL, Schroeder B, Shriver CD, Henning JD, Ellsworth RE.  “Chronic inflammation in cancer: the role of human viruses.”  Advances in Tumor Virology 2015(5):1-11.

Barrow TM, Barault L, Ellsworth RE, Harris HR, Binder AM, Valente AL, Shriver CD, Michels KB.  “Aberrant methylation of imprinted genes is associated with negative hormone receptor status in invasive breast cancer.”  International Journal of Cancer.  2015 August 1:137(3): 537-47.

Ellsworth RE, Toro AL, Blackburn HL, Decewicz A, Deyarmin B, Mamula KA, Costantino NS, Hooke JA, Shriver CD, Ellsworth DL.  “Molecular heterogeneity in primary breast carcinomas and axillary lymph node metastases assessed by genomic fingerprinting analysis.”  Cancer Growth Metastasis.  2015 July 20(8):15-24.

Rummel SK, Hueman MT, Costantino N, Shriver CD, Ellsworth RE.  “Tumor location within the breast: does tumor site have prognostic ability?” eCancermedicalscience, 2015 July 13(9):552.

Blackburn HL, Schroeder B, Turner C, Shriver CD, Ellsworth DL, Ellsworth RE.  “Management of incidental findings in the era of next-generation sequencing.”  Current Genomics.  2015 June; 16(3): 159-74.

Goodman CR, Sato T, Peck AR, Girondo MA, Yang N, Liu C, Yanac AF, Kovatich AJ, Hooke JA, Shriver CD, Mitchell EP, Hyslop T, Rui H.  “Steroid induction of therapy-resistant cytokeratin-5-positive cells in estrogen receptor-positive breast cancer through a BCL6-dependent mechanism.”  Oncogene.  2015 June 22. 

Chen Y, Bekhash A, Kovatich AJ, Hooke JA, Liu J, Kvecher L, Fantacone-Campbell JL, Mitchell EP, Rui H, Mural RJ, Shriver CD, Hu H.  “Positive association of fibroadenomatoid change with HER2-negative invasive breast cancer: a co-occurrence study.”  PLoS One.  2015 June 22;10(6):e0129500.

Toro AL, Constantino NS, Shriver, CD, Ellsworth, DL, Ellsworth, RE.  “Effect of obesity on molecular characteristics of invasive breast tumors: gene expression analysis of 405 tumors by BMI.” (submitted for publication clearance May 2015).

Rummel SK, Yarina W, Toro AL, Shriver CD, Ellsworth RE. “Differential gene expression in breast tumors from African American women: separating causation from stratification.” (submitted for publication clearance May 2015).

Rummel SK, Hueman MT, Costantino N, Shriver CD, Ellsworth RE.  “Association of tumor location within the breast and clinicopathological characteristics.”  American Association for Cancer Research, Annual Meeting, April 18-22, 2015, Philadelphia, PA.

Ellsworth RE, Mamula KA, Costantino NS, Deyarmin B, Kostyniak PJ, Chi LH, Shriver CD, Ellsworth DL.  “Abundance and distribution of polychlorinated biphenyls (PCBs) in breast tissue.”  Environmental Research.  2015 April;138: 291-7.

Constantino N, Toro AL, Shriver CD, Ellsworth EL, Ellsworth RE.  “Can a diagnosis of invasive breast cancer effectively motivate patients to follow a healthy lifestyle?” (submitted for publication clearance April 2015).

Iida J, Elisabeth T, Bell-Loncella TB, Purazo ML, Lu Y, Dorchak J, Clancy R, Slavick J, Ferrone S, Cutler ML, Shriver CD.  “Inhibition of cancer cell growth by ruthenium complexes.” (submitted for publication clearance March 2015).

Shriver CD, Hueman MT, Ellsworth RE. “Avoidance of surgical disruption of the axillary lymph nodes: can molecular profiling of primary breast tumors predict lymph node status?” Society of Surgical Oncology Annual Meeting, March 25-28, 2015, Houston, TX.

Blackburn HL, Ellsworth DL, Shriver CD, Ellsworth RE. “Role of cytochrome P450 genes in breast cancer etiology and treatment: effects on estrogen biosynthesis, metabolism and response to endocrine therapy.”  Cancer Causes and Control.  2015 March; 26(3):319-32.

Shriver CD, Hueman MT, Ellsworth RE.  “Avoidance of sentinel lymph node biopsy: can molecular profiling of primary breast tumors predict lymph node status?”  Society of Surgical Oncology Annual Cancer Symposium, March 25-28, 2015, Houston, TX.

Ellsworth RE, Valente AL, Blackburn HL, Decewicz A, Deyarmin B, Mamula K, Shriver CD, Ellsworth DL.  “Effect of genomic heterogeneity on breast cancer progression and metastatic spread.”  Society of Surgical Oncology Annual Cancer Symposium, March 25-28, 2015, Houston, TX.

Iida J, Dorchak J, Clancy R, Slavik J, Ellsworth R, Katagiri Y, Pugacheva EN, van Kuppevelt TH, Mural RJ, Cutler ML, Shriver CD.  “Role for chondroitin sulfate glycosaminoglycan in NEDD9-mediated breast cancer cell growth.”  Experimental Cell Research.  2015 Jan 15; 330(2):358-70.

Yarina WC, Field LA, Deyarmin B, van Laar R, Hooke JA, Shriver CD, Ellsworth RE.  “Molecular characterization of breast tumor-associated adipose.”  Cancer Research. 1 Jan 2015 75; B49.

Ellsworth RE, Valente AL, Hueman MT, Shriver CD.  “Pathological and molecular effects of lack of PR expression in ER positive breast tumors.”  Cancer Research. 1 May 2015 75; P3-04-12.  Annual CTRC-AACR San Antonio Breast Cancer Symposium; Dec 9-13, 2014, San Antonio, TX.

Shriver CD, Hueman MT, Ellsworth RE.  “Molecular signatures of lymph node status by intrinsic subtype: gene expression analysis of primary breast tumors from patients with and without metastatic lymph nodes.”  Journal of Experimental Clinical Cancer Research.  2014 Dec 31;33(1):782.

Ru Y, Mural R, Steeg PS, Rui H, Shriver CD, Hu H.  “Age independently predicts worse disease-specific survival in patients diagnosed with invasive breast cancers at 50 years of age or older but not younger.”  Annual CTRC-AARC San Antonio Breast Cancer Symposium, Dec 9-13, 2014, San Antonio, TX.

Ru Y, Lin J, Campbell JL, Zhu K, Kovatich AJ, Hooke JA, Kvecher L, Deyarmin B, Kovatich AW, Cammarata F, Rui H, Mural RJ, Shriver CD, Hu H.  “Survival comparative analysis of patients with invasive breast cancer treated by a military medical center and matched patients of the U.S. general population.”  Annual CTRC-AARC San Antonio Breast Cancer Symposium, Dec 9-13, 2014, San Antonio, TX.

Iida J, Purazo ML, Li Y, Bell-Loncella ET, Shriver CD.  “Structure-activity relationship of ruthenium (Ru) complexes to inhibit breast cancer growth and metastasis.”  Annual CTRC-AARC San Antonio Breast Cancer Symposium, Dec 9-13, 2014, San Antonio, TX.

Henning J, Oakes N, Valente AL, Deyarmin B, Meyer J, Hueman MT, Shriver CD, Ellsworth RE.  “Evaluation of the role of EBV in breast cancer.”  Annual CTRC-AARC San Antonio Breast Cancer Symposium, Dec 9-13, 2014, San Antonio, TX.

Joseph N, Kvecher L, Deyarmin B, Sturz L, Cammarata F, Larson C, Shriver CD, Mural RJ, Hu H.. “Tissue-experiment inventory: a system to enable cataloguing of experimental results in association with tissue and participant information.” American Medical Informatics Association (AMIA) Annual Symposium, Nov 15-19, 2014, Washington, DC.

Cammarata FJ, Kvecher L, Rui H, Kovatich AJ, Campbell LF, Hooke JA, Joseph NP, Shriver CD, Mural RJ, Hu H.  “A data repository system for translational research.” American Medical Informatics Association (AMIA) Annual Symposium, Nov 15-19, 2014, Washington, DC.

Schinkel JK, Zahm SH, Jatoi I, McGlynn KA, Gallagher C, Schairer C, Shriver CD, Zhu K. “Racial/ethnic differences in breast cancer survival by inflammatory status and hormonal receptor status: an analysis of the surveillance, epidemiology and end results data.” Cancer Causes and Control. 2014 Aug; 25(8):959-68.

Schinkel JK, Zahm SH, Jatoi I, McGlynn KA, Gallagher C, Schairer C, Shriver CD, Zhu K. “Racial/ethnic differences in breast cancer survival by inflammatory status and hormonal receptor status: an analysis of the Surveillance, Epidemiology and End Results data.”  Cancer Causes Control. 2014 Aug; 25(8):959-68. Doi: 10.1007/s10552-014-0395-1.

Valente AL, Rummel S, Shriver CD, Ellsworth RE. “Sequence-based detection of mutations in cadherin 1 to determine the prevalence of germline mutations in patients with invasive lobular carcinoma of the breast.”  Hered Cancer Clin Pract. 2014 Jul 19; 12(1):17. Doi:10.1186/1897-4287-12-17.

Enewold LR, McGlynn KA, Zahm SH, Poudrier J, Anderson WF, Shriver CD, Zhu K. “Breast reconstruction after mastectomy among Department of Defense beneficiaries by race.” Cancer. 2014 Jun 25. Doi: 10.1002/cncr.28806.

Valente AL, Kane JL, Ellsworth DL, Shriver CD, Ellsworth RE. “Molecular response of the axillary lymph node microenvironment to metastatic colonization.” Clin Exp Metastasis. 2014 Jun;31(5):565-72. doi: 10.1007/s10585-014-9650-9.

Sturtz LA, Deyarmin B, van Laar R, Yarina W, Shriver CD, Ellsworth RE. “Gene expression differences in adipose tissue associated with breast tumorigenesis.” Adipocyte. 2014 Apr 1;3(2):107-14. doi: 10.4161/adip.28250.

Valente AL, Shriver CD, Ellsworth RE. “Gene expression profiling of breast tumors from African American and Caucasian women: are molecular differences meaningful?” American Association for Cancer Research Annual Meeting, April 2014.

Gallagher C, More K, Hu H, Sicignano N, Masaquel A, Kamath T, Brammer M, Shriver CD, Goehring E, Kapasi A, Jones J. “Discordance rate between two tests used to diagnose patients with HER2-overexpressing breast cancer.” AMCP Conference, 1-4 April 2014, Tampa, FL.

Rummel S, Penatzer CE, Shriver CD, Ellsworth RE. “PSPHL and breast cancer in African American women: causative gene or population stratification?”  BMC Genet. 2014 Mar 20;15:38. doi: 10.1186/1471-2156-15-38.

Maskery S, Bekhash A, Kvecher L, Correll M, Hooke JA, Kovatich AJ, Shriver CD, Mural RJ, and Hu H. “Aggregated biomedical-information browser (ABB): a graphical user interface for clinicians and scientists to access a clinical data warehouse” Journal of Computer Science & Systems Biology. February 2014.

Iida J, Clancy R, Dorchak J, Somiari RI, Somiari S, Cutler ML, Mural RJ, Shriver CD.  “DNA aptamers against exon v10 of CD44 inhibit breast cancer cell migration.” PLoS One. 2014 Feb 19;9(2):e88712. doi: 10.1371/journal.pone.0088712.

Greenspan R, O’Donnell A, Meyer J, Kane J, Mamula K, Deyarmin B, Larson C, Rigby S, Sturz LA, Lelley J, Shriver CD, Ellsworth RE. “Outcome disparities in African American women with triple negative breast cancer: a comparison of epidemiological and molecular factors between African American and Caucasian women with triple negative breast cancer” BMC Cancer. 2014 February 2014.

Sturtz LA, Melley J, Mamula K, Shriver CD, Ellsworth RE. “Outcome disparities in African American women with triple negative breast cancer: a comparison of epidemiological and molecular factors between African American and Caucasian women with triple negative breast cancer.” BMC Cancer. 2014 Feb 4;14:62.

Greer LT, Rosman M, Charles Mylander W, Liang W, Buras RR, Chagpar AB, Edwards MJ, Tafra L. “A prediction model for the presence of axillary lymph node involvement in women with invasive breast cancer: a focus on older women” Breast Journal, 30 January 2014.