Breast Cancer Risk Reduction

CBCP’s Risk Reduction Clinic at WRNMMC is a multi-disciplinary program designed to identify, counsel and manage women at high risk for breast cancer.  Patients receive an in-depth personal and family health history by our geneticist, genetics nurse and genetics counselor. 

Current research shows there are risk factors that may influence the development of breast cancer. Identifying people with these risk factors and implementing closer surveillance and risk reduction techniques may detect cancer earlier. Earlier detection of breast cancer leads to better prognosis and outcomes. Calculations of risk are based on computer models extensively validated as accurate in identifying women at high risk.

All female patients age 18 and older, seen in the Breast Care Center will have the option of consenting to two CBCP protocols: Tissue and Blood Library Establishment for Molecular, Biochemical, and Histologic Study of Breast Disease protocol or the Creation of Blood Library for the Analysis of Blood for Molecular Changes Associated with Breast Disease and Breast Cancer Development protocol.

Patients being seen in the CBCP Breast Care Center at WRNMMC or at the JMBCC in Windber, PA will be assessed for their risk of developing breast cancer by their history of LCIS or ADH or by applying the NCI Breast Cancer Risk Assessment Tool. Identified high-risk patients will be referred to the CBCP Risk Reduction Clinic. Patients are confirmed to meet the inclusion criteria and consented to one of two core protocols.   Information collected will include the data contained on the enclosed database forms and may include data from previous clinic visits. All applicable patients will be followed indefinitely according to the applicable protocol.

If patients are referred for genetic testing, as per the American Society of Clinical Oncology, counseling involves the following eleven points:

  1. Information on the specific test being performed
  2. Implications of positive and negative results
  3. Options for estimation without genetic testing
  4. Risk of passing a mutation to a child
  5. Technical accuracy of the test
  6. Possibility that the test will not be informative
  7. Fees involved in testing
  8. Risk of psychological distress
  9. Risk of insurance or employer discrimination
  10. Confidentiality issues
  11. Options for medical surveillance and screening following testing